Director, Enterprise IT Infrastructure
The Andrews Group
Other Engineering, IT
Posted on Feb 13, 2026
Eversight
Enterprise Infrastructure Director
Position Summary
The Enterprise Infrastructure Director serves as the organization’s senior technical authority responsible for analyzing, designing, and optimizing enterprise systems and application architecture. This role operates as a high-impact individual contributor, providing strategic and hands-on leadership to reduce system complexity, improve efficiency, strengthen security, and ensure technology investments align with organizational priorities.
The Enterprise Infrastructure Director works cross-functionally to influence decision-making, set technical standards, and guide vendors, consultants, and internal stakeholders.
Key Responsibilities
Enterprise Architecture & Systems Optimization
- Evaluate current IT infrastructure, applications, integrations, and data flows to identify redundancy, inefficiencies, and technical debt.
- Design and maintain a scalable, secure, and sustainable target-state architecture.
- Develop roadmaps to simplify systems, consolidate platforms, and improve interoperability.
- Establish architectural principles and technical standards to guide technology decisions.
Technology Strategy & Governance
- Partner with executive leadership to align technology strategy with organizational goals.
- Assess proposed technology investments for architectural fit, long-term viability, and total cost of ownership.
- Serve as the technical authority for system design decisions and exception approvals.
- Create and maintain documentation of systems architecture, dependencies, and risk areas.
Vendor & Platform Oversight
- Provide technical oversight of vendors, Managed Service Providers, and SaaS providers.
- Evaluate vendor solutions for security, scalability, integration capability, and cost efficiency.
- Participate in contract reviews, renewals, and RFPs from a technical and architectural perspective.
- Hold vendors accountable to performance, security, and service expectations.
Systems & Data Management
- Ensure data integrity, accuracy, availability, and traceability across clinical, donor, inventory, logistics, finance, HR, and reporting systems.
- Lead efforts to integrate disparate systems to enable real-time reporting, analytics, and decision-making.
- Project manage software upgrades or migrations to new platforms (e.g., accounting).
- Establish governance for master data management, data standards, and system ownership.
Regulatory Compliance & Risk Management
- Ensure IT systems support compliance with FDA, EBAA, HIPAA, and other applicable regulatory and accreditation standards.
- Partner with Quality and Compliance teams on audits, inspections, validation documentation, and corrective action plans.
- Oversee cybersecurity, disaster recovery, business continuity planning, and incident response.
Supervisory Responsibilities
- Data Analytics Director
- Systems Administrator
Required Qualifications
- Bachelor’s degree in Information Technology, Computer Science, Health Informatics, or related field (Master’s preferred).
- 8–10+ years of progressive IT leadership experience, including enterprise systems oversight.
- Demonstrated experience managing complex, multi-platform environments with significant integration challenges.
- Experience in healthcare, life sciences, tissue banking, or other regulated clinical environments strongly preferred.
- Proven success driving system standardization, integration, and data governance initiatives.
Preferred Skills & Competencies
- Strategic thinker with strong business acumen and change management skills.
- Deep understanding of data integrity, system validation, cybersecurity, and compliance frameworks.
- Experience with clinical, laboratory, ERP, CRM, and reporting/BI platforms.
- Ability to balance mission-driven values with operational discipline and fiscal responsibility.
- Strong communication skills and credibility with executives, clinicians, and external partners.